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Exhaustion – increased iron intake can help

Iron deficiency impairs oxygen transport in the body which can cause fatigue

Increased iron intake can reduce exhaustion

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Iron deficiency usually affects women, but men can also be affected, especially runners.
Iron deficiency, primarily due to inadequate dietary iron intake, is considered the most common nutritional deficiency leading to anaemia. Deficiencies in vitamin A, vitamin B9/B12 can also result in anaemia due to their specific roles in the synthesis of haemoglobin.
Iron deficiency can lead to fatigue, headaches, depression, or anxiety.

Calcium prevents the absorption of iron, if the purpose is to increase iron in the body, calcium should be avoided 1 hour before and after iron intake.

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There are different types of iron in both food and supplements.
-Heme iron is found in meat, fish, and poultry. Heme iron is the most bioavailable form of iron, as up to 40% of it is readily absorbed by your body.
-Non-heme iron primarily comes from plant sources and is present in grains, vegetables and fortfed foods. In terms of its bioavailability, non-heme iron is absorbed much less efciently, only 2-5%.
-Artificial non-heme iron in medicine that also has low bioavailability often has added vitamin-C but it often causes stomach problems.

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Low iron levels can be diagnosed through regular blood tests. If the doctor does not want to do all the necessary tests, there are many private laboratories that can perform blood tests for iron.
+ Hemoglobin – protein in blood holds oxygen
+ Leukocyter- amount white blood cells
+ MCV – value related to your red blood cells
+ Ferritin – storage capacity of iron in body
+ Iron – measures circulatng iron in blood
+ Transferrin – liver secretes this for iron absorption from food

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After reading research on iron deficiency, I showed my doctor that the low Ferritin values and low Transferrin in blood tests may be the cause of iron deficiency and fatigue.
But the doctor said that many people have low values and still feel good.
Since the doctor didn’t listen to me, I started eating heme iron, but I ate less than the daily recommendation, it was due to low Transferrin value from the liver which showed that the body had difficulty absorbing iron.
After a few months of heme iron, the Ferritin value had finally increased by the end of the year 2024 and it improved health.

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Professor Allen says that we are different,  some are tall, others short, we have different eating habits, and therefore some may need more iron than others to feel good. Ferritin levels should be above 75 in those with restless legs according to research. Allen says that some may even need a Ferritin value of 150 to feel good.

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If the liver gives a low Transferrin value, the body often absorbs little iron regardless of how much iron is in the food. In case of illness, the Transferrrin value decreases, but if it is continuously low, it may be because the liver’s function is impaired by:
-inflammation
-stress
-heavy metals
-alcohol
-trauma
Researchers of trauma call it “Post Traumatic Inflammation”, a deep trauma that also affects the condition of the liver.
Researchers say that reducing the intake of sodium salt reduces strain on the liver and kidney.

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Research and references Iron
 

Ef: Nagaraju, S.P., Cohn, A., Akbari, A. et al. Heme iron polypeptide for the treatment of iron defciency anemia in non-
dialysis chronic kidney disease patients: a randomized controlled trial. BMC Nephrol 14, 64 (2013) doi:10.1186/1471-
2369-14-64

Fisher AE, Naughton DP. Iron supplements: the quick fx with long-term consequences. Nutr J. 2004;3:2. Published 2004
Jan 16. doi:10.1186/1475-2891-3-2

Li Y, Jiang H, Huang G. Protein Hydrolysates as Promoters of Non-Haem Iron Absorption. Nutrients. 2017;9(6):609.
Published 2017 Jun 15. doi:10.3390/nu9060609

Guo L., Harnedy P.A., Li B., Hou H., Zhang Z., Zhao X., Fitzgerald R.J. Food protein-derived chelating peptides:
Biofunctional ingredients for dietary mineral bioavailability enhancement. Trends Food Sci. Technol. 2014;37:92–105.
doi: 10.1016/j.tifs.2014.02.007

Bacchetta J, Zaritsky JJ, Sea JL, et al. Suppression of iron-regulatory hepcidin by vitamin D. J Am Soc Nephrol.
2014;25(3):564–572. doi:10.1681/ASN.2013040355

Fisher AE, Naughton DP. Iron supplements: the quick fx with long-term consequences. Nutr J. 2004;3:2. Published 2004
Jan 16. doi:10.1186/1475-2891-3-2

Richard Hurrell, Ines Egli, Iron bioavailability and dietary reference values, The American Journal of Clinical Nutriton,
Volume 91, Issue 5, May 2010, Pages 1461S–1467S

Hooda J, Shah A, Zhang L. Heme, an essential nutrient from dietary proteins, critically impacts diverse physiological and
pathological processes. Nutrients. 2014;6(3):1080–1102. Published 2014 Mar 13. doi:10.3390/nu6031080

Björn-Rasmussen E, Hallberg L, Isaksson B, Arvidsson B. Food iron absorption in man. Applications of the two-pool
extrinsic tag method to measure heme and nonheme iron absorption from the whole diet. J Clin Invest. 1974;53(1):247–
255. doi:10.1172/JCI107545

Hernik A, Szczepanek-Parulska E, Filipowicz D, et al. Hepcidin and Iron Homeostasis in Patients with Subacute Thyroiditis
and Healthy Subjects. Mediators Infamm. 2019;2019:5764061. Published 2019 Feb 27. doi:10.1155/2019/5764061

Young I, Parker HM, Rangan A, et al. Association between Haem and Non-Haem Iron Intake and Serum Ferritin in
Healthy Young Women. Nutrients. 2018;10(1):81. Published 2018 Jan 12. doi:10.3390/nu10010081

Ueda N, Takasawa K. Impact of Infammation on Ferritin, Hepcidin and the Management of Iron Defciency Anemia in
Chronic Kidney Disease. Nutrients. 2018;10(9):1173. Published 2018 Aug 27. doi:10.3390/nu10091173

 

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